We selected 18 samples which were analyzed by using MeDIP-seq and MRE-seq in Roadmap Epigenomics project, then appied methylMnM to discover Differential Methylated Regions(DMRs) at tissue level, cell type level, and individual level. The details could be found in...
You could also browser all DNA methylome and DMRs in genome browser: epigenome.wustl.edu
18 samples belongs to 4 tissue types: H1 ESC, blood, breast, and brain.
|H1 ESC||Adult Blood||Adult Breast||Fetal Brain|
Cell type-specific DMRs
Here we only show two sets of cell type-spcific DMRs: Breast Myoepithelial Vs. Breast Luminal epithelial; and CD4 Naive cell Vs. CD4 memory cell.
|CD4 Naive cell||CD4 memory cell|
In 18 samples, 16 came from 6 indivudals. Here we show individual-specific DMRs in 3 paired individuals
|DMRs in adult blood||DMRs in adult breast||DMRs in fetal brain|
|Number of DMRs||310||55||307|